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2019-06-23 at 05:30AM UTC #280536
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La terapia de tapentadol combinación mediante el uso de agonistas del receptor opioide µ, junto a inhibidores de la recaptación de noradrenalina, ha ido ganando adeptos durante los últimos años, como alternativa para tratar los diversos mecanismos que subyacen al dolor neuropático .
No obstante, si bien los fármacos inhibidores de la recaptación de noradrenalina son bien tolerados, su eficacia analgésica a menudo no es satisfactoria, y, por su parte, los opioides suelen ofrecer problemas de tolerabilidad; recientemente se ha introducido en el mercado el tapentadol, que combina en una misma molécula acciones tapentadol de Results and Conclusions .
The therapeutic combination of the μ opioid receptor agonists with inhibitors of the norepinephrine reuptake have become more popular recently tapentadol as an alternative to treat the mechanisms responsible for neuropathic pain .
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