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2019-07-12 at 10:53AM UTC #282015
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The most common treatment emergent adverse events (≥10% of patients in either treatment group) were constipation, nausea, dizziness, somnolence, vomiting, headache, fatigue and tapentadol pruritus .
6%) tapentadol than in the oxycodone controlled release group (21 . The incidence of gastrointestinal treatment emergent adverse events, including nausea, vomiting or constipation, that led to study discontinuation was lower in the tapentadol tapentadol prolonged release group (8 .

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