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2019-06-28 at 02:02PM UTC #281040
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Spermatidic giant cells were observed in monkeys after 6month treatment at 30 mg/kg/day in addition to crestor vacuolation of seminiferous tubular epithelium .
Exposures in the dog were 20 times and in the monkey 10 times human exposure crestor dangerous side effects does crestor cause weight gain sandoz rosuvastatin vs crestor generic at 40 mg/day based on body surface area comparisons .
Similar findings side effects of crestor rosuvastatin side effect of crestor medicine crestor med crestor 40 mg side have been seen with other drugs in this Pregnancy Category X See CONTRAINDICATIONS .
Rosuvastatin may cause fetal harm when administered to a crestor pregnant woman .
Rosuvastatin is contraindicated in crestor women who are or may become pregnant .
Safety in pregnant women has crestor not been established .
There are no adequate and well-controlled studies of rosuvastatin in pregnant does crestor cause insomnia crestor mechanism of action generic for crestor 10 mg crestor 5mg women .
Rosuvastatin crosses the placenta and is found in fetal tissue and amniotic fluid at 3% and 20%, respectively, of the maternal plasma concentration following a single 25 mg/kg oral crestor gavage dose on gestation day 16 in rats .
A higher fetal tissue distribution (25% maternal plasma concentration) was observed in rabbits after a single crestor oral gavage dose of 1 mg/kg on gestation day 18 .
If this drug is administered to a woman crestor with reproductive potential, the patient should be apprised of the potential hazard to a fetus .
In female rats given oral gavage doses of 5, 15, 50 mg/kg/day rosuvastatin before mating and continuing through day 7 postcoitus results in decreased fetal body weight (female pups) and crestor delayed ossification at the high dose (systemic exposures 10 times human exposure at 40 mg/day based on AUC comparisons) .

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